LeMoyne-Owen College (LOC or "LeMoyne-Owen") is a private historically black college affiliated with the United Church of Christ and located in Memphis, Tennessee. It resulted from the 1968 merger of historically black colleges and other schools established by northern Protestant missions during and after the American Civil War.

LeMoyne-Owen College is a private institution that was founded in 1862. It has a total undergraduate enrollment of 835, its setting is urban, and the campus size is 15 acres.